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Impaired activation of Stat1 and c-Jun as a possible defect in macrophages of patients with active tuberculosis
Clinical and Experimental Immunology, 09/10/09
Esquivel–Solis H et al. – These results indicate an impairment of Stat1–dependent and Stat1–independent IFN–gamma signalling in macrophages of people with active tuberculosis, suggesting a different molecular regulation that could impact macrophage functionality and disease outcome.
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Today in Basic Science/Genetics...keeping you current
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