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See Latest ArticlesA threshold level of TLR9 mRNA predicts cellular responsiveness to CpG-ODN in haematological and non-haematological tumour cell lines
Cellular Immunology, 09/14/09
Assaf A et al. – CpG–ODN induced NF?B activation and increased cellular proliferation in Hek293 cells that had been stably transfected with hTLR9, but did not affect the expression of surface markers or synthesis of IL–6, IL–10 or TNF–alpha. Thus both haematological and non–haematological cells expressing appropriate levels of TLR9 respond to CpG–ODN, but the nature of the TLR9–mediated response is dependent on cell type.
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The regulatory role of the MisR/S two-component system in hemoglobin utilization in Neisseria meningitidis
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Today in Hematology/Oncology...keeping you current
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