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Isoniazid in patient plasma may cause a false-positive result on the complement-dependent cytotoxicity test
Human Immunology, 09/02/09
Poli F et al. – The authors postulated that nonspecific binding of drug–antibody complexes to panel lymphocytes in the CDC test may have caused the observed lympholysis. This case, although isolated, emphasizes the importance of the combined use of CDC and solid phase assays. The CDC results alone would have led to the erroneous conclusion that the patient was highly sensitized.
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