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Vlad G et al. – Using a hu–nonobese diabetic/severe combined immunodeficiency (hu–NOD/SCID) gamma–null model of xenogeneic GVHD, the authors have demonstrated that treatment with recombinant immunoglobulin–like transcript 3–Fc protein induces the differentiation of CD8+ T suppressor cells and blocks the cellular and humoral arm of the GVH reaction.


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