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Improving administration regimens of CyaA-based vaccines using TRAP assays to detect antigen-specific CD8+ T cells directly ex vivo
Vaccine , 09/11/09
Daubeuf S et al. – The authors find that the intradermal, intramuscular or subcutaneous routes are all superior to intravenous injections, and actually lead to a sufficiently high frequency of reactive CTL to be detected and characterized directly ex vivo by TRAP assay or other standard assays.
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