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See Latest ArticlesA simple two-step culture system for the large-scale generation of mature and functional dendritic cells from umbilical cord blood CD34+ cells
Transfusion, 09/11/09
Balan S et al. – A two–step culture system provides a large–scale expansion of CD34+ cells with a preferential lineage commitment toward CD14+ cells. Enrichment of these precursors with a simple plastic adherence technique results in generation of large numbers of mature, functional DCs. This method of in vitro DC generation will have applications in cancer immunotherapy.
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