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Efficacy, Tolerance, and Safety of Mammalian Target of Rapamycin Inhibitors as Rescue Immunosuppressants in Liver Transplantation
Transplantation Proceedings, 09/01/09
Alamo JM et al. – MTOR inhibitors were safe immunosuppressive drugs whose side effects were controlled and easily managed. They have advantages with respect to CNI due to their slight effects on kidney function and lack of promotion of diabetes mellitus. Although their long–term effectiveness for control of neoplastic diseases is yet to be seen, they can be used safely in these patients with no incidence of rejection. Their effectiveness to control chronic rejection seems significant, but it is doubtful for steroid–resistant acute rejection episodes.
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Today in Gastrointestinal/Hepatic...keeping you current
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Leishmania donovani-induced expression of signal regulatory protein [alpha] on Kupffer cells enhances hepatic invariant NKT-cell activation
European Journal of Immunology, 12/11/09
Hepatitis A virus antibodies in immunoglobulin preparations
Journal of Allergy and Clinical Immunology, 12/08/09
Cycling of gut mucosal CD4+ T cells decreases after prolonged anti-retroviral therapy and is associated with plasma LPS levels
Mucosal Immunology, 12/07/09
Today in Surgery/Transplantation...keeping you current
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T cell receptor beta chain (TCR-V-beta) repertoire of circulating CD4+ CD25?, CD4+ CD25low and CD4+ CD25high T cells in patients with long-term renal allograft survival
Transplant International, 12/11/09
Activation, Immune Polarization, and Graft-versus-Leukemia Activity of Donor T Cells Are Regulated by Specific Subsets of Donor Bone Marrow Antigen-Presenting Cells in Allogeneic Hemopoietic Stem Cell Transplantation
Journal of Immunology, 12/11/09
Allogeneic Hematopoietic Stem-Cell Transplantation for Sickle Cell Disease
New England Journal of Medicine, 12/10/09
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