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Global H4 acetylation analysis by ChIP-chip in systemic lupus erythematosus monocytes
Genes and Immunity, 08/28/09
Zhang Z et al. – IRF1 binding sites were also upstream of nearly all genes with both increased H4ac and gene expression. Alpha–IFN was a significant contributor to both expression and H4ac patterns, but the greatest concordance was seen in the enrichment of certain transcription factor binding sites upstream of genes with increased H4ac in SLE and genes with increased H4ac after alpha–IFN treatment.
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