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The C-Type Lectin-Like Receptor CLEC-1, Expressed by Myeloid Cells and Endothelial Cells, Is Up-Regulated by Immunoregulatory Mediators and Moderates T Cell Activation
Journal of Immunology, 08/24/09
Thebault P et al. – The data suggest that CLEC–1, expressed by myeloid cells and endothelial cells, is enhanced by regulatory mediators and moderates Th17 differentiation. Therefore, CLEC–1 may represent a new therapeutic agent to modulate the immune response in transplantation, autoimmunity, or cancer settings.
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