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Nasal CpG oligodeoxynucleotide administration induces a local inflammatory response in nonallergic individuals
Allergy, 08/19/09
Mansson A et al. – Nasal administration of CpG induces a local airway inflammation, more distinct among healthy than allergic individuals. The reduced responsiveness to CpG in allergic patients might be related to the ongoing minimal persistent inflammation. Results from cytokine analyses reflect the ability of CpG to induce a pro–inflammatory Th1–like immune response.
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