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See Latest ArticlesA novel approach to induce human DCs from monocytes by triggering 4-1BBL reverse signaling
International Immunology, 08/17/09
Ju S et al. – The authors have further demonstrated that anti–4–1BBL antibody stimulated nuclear translocation of NF–kB from the cytoplasm in monocytes, suggesting that reverse signaling by 4–1BBL is likely responsible for mediating DC differentiation. Collectively, authors have found that reverse signaling of 4–1BBL promotes the differentiation of potent Th1–inducing DCs from human monocytes.
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Today in Hematology/Oncology...keeping you current
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