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Ficolin 2 (FCN2) functional polymorphisms and the risk of rheumatic fever and rheumatic heart disease
Clinical and Experimental Immunology, 08/17/09

Messias–Reason IJ et al. – The haplotype –986/–602/–4 A/G/A was observed more frequently in the healthy group when compared to the affected subjects. Based on those findings, one can conclude that polymorphisms associated with low levels of L–ficolin level may predispose an individual to recurrent and/or more severe streptococcal infection.

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