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Induction of a disintegrin and metalloprotease 33 during embryonic lung development and the influence of IL-13 or maternal allergy
Journal of Allergy and Clinical Immunology, 08/17/09
Michael Haitchi H et al. – Adam33/Adam33 shows 2 significant increments in expression during lung morphogenesis, suggesting important developmental regulation. The ability of maternal allergy or exogenous IL–13 to suppress Adam33/ADAM33 mRNA but enhance Adam33 processing suggests a gene–environment interaction that may be relevant for asthma pathogenesis.
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