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See Latest ArticlesCytotoxicity and secretion of IFN-gamma are carried out by distinct CD8 T cells during Mycobacterium tuberculosis infection
Infection and Immunity, 08/24/09
Einarsdottir T et al. – Memory CD8 T cells responded earlier and reached higher levels in the lungs than naïve CD8 T cells, as would be expected. They were, however, less cytotoxic and secreted less IFN–gamma than newly primed CD8 T cells, suggesting that one factor contributing to bacterial persistence and lack of sterilizing immunity may be the low quality of memory cells that are generated.
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Today in Basic Science/Genetics...keeping you current
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Today in Cardiovascular/Pulm...keeping you current
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