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Functional Modulation of Dendritic Cells and Macrophages by Japanese Encephalitis Virus through MyD88 Adaptor Molecule-Dependent and -Independent Pathways
Journal of Immunology, 08/14/09
Aleyas AG et al. – Data suggest that JEV induces functional impairment of DCs through MyD88–dependent and –independent pathways, which subsequently leads to poor CD4+ and CD8+ T cell responses, resulting in boosting viral survival and dissemination in the body.
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