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Intravenous immunoglobulin therapy for autoimmune diseases
Autoimmunity, 08/06/09

Arnson Y et al. – The increasing availability of modern biological therapies has advanced the ability to target and to neutralize essential components of the immune response without experiencing the hazardous adverse effects caused by the traditional immunosuppressants. One of the noticeable examples of this approach is the increasing use of high–dose intravenous immunoglobulin. IVIg mechanisms include modulating function of Fc receptors, interference with complement activation and cytokine network, provision of anti–idiotypic antibodies, regulation of cell growth, and effects on of T and B cells.

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