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IL-17-producing CD8+ T lymphocytes from psoriasis skin plaques are cytotoxic effector cells that secrete Th17-related cytokines
Journal of Leukocyte Biology, 08/11/09
Ortega C et al. – CD8+IL–17+ T cells share some key features with Th17 cells and exhibit remarkable differential abilities attributable to the CD8+ lineage of T lymphocytes, adding new insights into the functional resources of IL–17–producing cells from human epidermis that could be of potential interest to the understanding of the pathogenesis of psoriasis.
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