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Differential Dose Adjustments of Immunosuppressants after Resuming Boosted versus Unboosted HIV-Protease Inhibitors Postliver Transplant
American Journal of Transplantation, 08/04/09
Guaraldi G et al. – The primary objective of this study was to evaluate the decreases in IS dosages necessary to maintain an appropriate therapeutic window (TW) after initiating PI–based antiretroviral therapy regimens post–LTx. The overall median time necessary to reach IS TW after dose adjustment was 3.5 days (range 0–15). Unboosted PIs exhibited lesser PK interactions with IS than did RTV–boosted PIs and were thus more amenable to use in the post–LTx setting.
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Today in Gastrointestinal/Hepatic...keeping you current
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The Salmonella enterica serotype Typhi Vi capsular antigen is expressed after entering the ileal mucosa
Infection and Immunity, 11/25/09
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Today in Surgery/Transplantation...keeping you current
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Effects of Prophylactic Splenic Artery Modulation on Portal Overperfusion and Liver Regeneration in Small-for-Size Graft
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