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Molecular modeling and epitopes mapping of human adenovirus type 3 hexon protein
Vaccine , 08/10/09
Yuan X et al. – Finally five polypeptides were synthesized and the predicted epitopes were identified by enzyme–linked immunosorbent assay and Neutralization Test. It was found that the type–specific neutralizing epitopes of HAdV3 are located at the top surface of hexon tower regions. This work is of great significance to the molecular design of a multivalent HAdVs vaccine.
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