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Memory impairment induced by IL-1 beta is reversed by alpha-MSH through central melanocortin-4 receptors
Brain, Behavior, and Immunity, 07/30/09
Gonzalez PV et al. – Treatment with alpha–MSH blocked the effect of IL–1 beta on contextual fear memory. Administration of the MC4 receptor antagonist HS014 reversed the effect of alpha–MSH. However, treatment with gamma–MSH, an MC3 agonist, did not affect IL–1 beta–induced impairment of memory consolidation. These results suggest that alpha–MSH, through central MC4R can inhibit the effect of IL–1 beta on memory consolidation.
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Retinal astrocytes respond to IL-17 differently than retinal pigment epithelial cells
Journal of Leukocyte Biology, 12/04/09
Limited Role of CD4+Foxp3+ Regulatory T Cells in the Control of Experimental Cerebral Malaria
Journal of Immunology, 12/04/09
Tyrosine Kinase 2 Plays Critical Roles in the Pathogenic CD4 T Cell Responses for the Development of Experimental Autoimmune Encephalomyelitis
Journal of Immunology, 12/04/09
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