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Viera L et al. – This article reviews the evidence supporting the fundamental role of air pollutants in fostering allergic inflammation of the airways, with emphasis on the molecular and genetic pathways that link ambient particulate matter (PM) exposure to the induction of proinflammatory changes and proallergic effects in the respiratory tract. The authors propose that the link between PM exposure and proallergic effects involves organic PM components that generate oxygen radicals capable of perturbing the redox equilibrium mucosal immune cells.

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