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Basophil responsiveness in chronic urticaria
Current Allergy and Asthma Reports, 08/06/09
Saini SS – In active chronic idiopathic urticaria (CIU) subjects, changes in IgE receptor–signaling molecule expression levels accompany the altered degranulation function in blood basophils. The arrival of therapies targeting IgE has further shown that altered blood basophil degranulation behavior has potential use as a disease biomarker in CIU.
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