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Plasmapheresis and Intravenous Immune Globulin Provides Effective Rescue Therapy for Refractory Humoral Rejection and Allows Kidneys To Be Successfully Transplanted Into Cross-Match-Positive Recipients
Transplantation, 07/23/09
Montgomery RA et al. – In this study, the authors present seven patients for whom the combined therapies of PP/IVIG were successful in reversing AHR mediated by Ab specific for donor HLA antigens. Furthermore, this protocol shows promise for eliminating DSA preemptively among patients with low–titer positive antihuman globulin–enhanced, complement–dependent cytotoxicity (AHG–CDC) cross–matches, allowing the successful transplantation of these patients using a live donor without any cases of HAR.
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