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Spontaneous Autoimmunity Sufficiently Potent to Induce Diabetes Mellitus Is Insufficient to Protect against Insulinoma
Journal of Immunology, 07/22/09
Zwicker K et al. – Alterations in the tumor microenvironment may inhibit efficient and comprehensive delivery of CD8+ T cells to all regions of the tumor. These data suggest that any immunotherapeutic strategy for cancer must involve enhancement of a proinflammatory tumor microenvironment in addition to inhibition of tolerogenic mechanisms.
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Today in Basic Science/Genetics...keeping you current
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Recipient NOD2/CARD15 status affects cellular infiltrates in human intestinal graft-versus-host disease
Clinical and Experimental Immunology, 12/04/09
Milder clinical hyperimmunoglobulin E syndrome phenotype is associated with partial interleukin-17 deficiency
Clinical and Experimental Immunology, 12/04/09
Effects of PARP-1 deficiency on airway inflammatory cell recruitment in response to LPS or TNF: differential effects on CXCR2 ligands and Duffy antigen receptor for chemokines
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Today in Endocrine...keeping you current
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The Multi-faceted Influences of Estrogen on Lymphocytes: Toward Novel Immuno-interventions Strategies for Autoimmunity Management
Clinical Reviews in Allergy and Immunology, 12/03/09
Gene expression profiles for the human pancreas and purified islets in Type 1 diabetes: new findings at clinical onset and in long-standing diabetes
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