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Comparative analysis of the properties and ligand binding characteristics of CspZ, a factor H binding protein, derived from Borrelia burgdorferi isolates of human origin
Infection and Immunity, 07/27/09

Rogers EA et al. – The data presented within provide significant new insight into the interaction between CspZ and FH, and suggest a correlation between CspZ production and dissemination. However, in spite of its possible contributory role in pathogenesis, the immunological analyses indicated that CspZ is likely to be of limited potential as a diagnostic marker and vaccine candidate for Lyme disease.

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