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Rituximab is an effective treatment for lupus nephritis and allows a reduction in maintenance steroids
Nephrology Dialysis Transplantation, 07/20/09
Pepper R et al. – Lupus nephritis is a life–threatening complication of SLE. Treatment regimes include steroids and cyclophosphamide, both associated with significant morbidity. The data demonstrates the efficacy of a rituximab and MMF based regime in the treatment of lupus nephritis, allowing a reduction or total withdrawal of corticosteroids.
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