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See Latest ArticlesSimvastatin Inhibits Airway Hyperreactivity: Implications for the Mevalonate Pathway and Beyond
American Journal of Respiratory and Critical Care Medicine, 07/21/09
Zeki AA et al. – Simvastatin attenuates allergic airway inflammation, inhibits key Th1 and Th2 chemokines, and improves lung physiology. The mevalonate pathway appears to modulate allergic airway inflammation, while the beneficial effects of simvastatin on lung compliance and airway hyperreactivity may be independent of the mevalonate pathway. Simvastatin and similar agents that modulate the mevalonate pathway may prove to be treatments for inflammatory airway diseases, such as asthma.
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Today in Cardiovascular/Pulm...keeping you current
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Decreased Levels of Secretory Leucoprotease Inhibitor in the Pseudomonas-Infected Cystic Fibrosis Lung Are Due to Neutrophil Elastase Degradation
Journal of Immunology, 12/15/09
CD69 Controls the Pathogenesis of Allergic Airway Inflammation
Journal of Immunology, 12/15/09
IL-1R1/MyD88 Signaling Is Critical for Elastase-Induced Lung Inflammation and Emphysema
Journal of Immunology, 12/15/09
Today in Clinical Pharmacology...keeping you current
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Is There a Role for B-cell Depletion as Therapy for Scleroderma? A Case Report and Review of the Literature
Seminars in Arthritis and Rheumatism, 12/15/09
Reduction of the Occurrence of Acute Cellular Rejection Among Renal Allograft Recipients Treated With Basiliximab, A Chimeric Anti-Interleukin-2-Receptor Monoclonal Antibody
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The use of anti-D immunoglobulins for rhesus prophylaxis: audit on knowledge and practices among obstetricians
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