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See Latest ArticlesFetal membranes exhibit selective leukocyte chemotaxic activity during human labor
Journal of Reproductive Immunology, 07/10/09
Gomez-Lopez N et al. - The same extracts elicited a significant increase in attracted monocytes as well as T and B lymphocytes, and NK cells when compared to extracts from women without labor. This enhanced chemotactic activity was associated with the presence of IL-8, MCP-1, IP-10 and MIP-1 alpha. The authors conclude that fetal membrane extracts obtained from women during labor exhibit selective chemotaxis for specific leukocyte subpopulations in vitro. This process may contribute to a microenvironment composed of specific leukocytes that promotes and amplifies biochemical changes in the fetal membranes during labor.
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