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See Latest ArticlesExpression of NK cell receptors on decidual T cells in human pregnancy
Journal of Reproductive Immunology, 07/10/09
Tilburgs T et al. - Decidual KIR+ and CD94-NKG2+ T cells mainly display a CD3+CD4-CD8- phenotype. However, decidual tissue also contains higher percentages of KIR and CD94-NKG2 expressing CD4+ and CD8+ T cells compared to peripheral blood. So far, the functional capacities of decidual T cells expressing the NK cell receptors are unknown but NK cell receptor expression on decidual T cells may provide an alternative means by which decidual T cells distinguish self cells from allogeneic fetal cells, and act to modulate the decidual immune response.
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