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Apo material as a trigger for inflammation in systemic lupus erythematosus
Autoimmunity, 07/08/09
Meesmann HM et al. - Recent publications link alpha IFN and apo: apo cell-derived microparticles can directly stimulate plasmacytoid dendritic cells to secret alpha IFN. This review highlights the role of apo material as source for AAg and as a trigger for chronic inflammation in the pathogenesis of SLE.
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