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Development of immunization approaches to amyotrophic lateral sclerosis
Future Neurology, 07/08/09
Gros-Louis F et al. - Prophylactic immunotherapy may become a conceivable approach for SOD1-linked ALS patients providing that the treatment is not overly invasive and can be implemented at reasonable cost. This article reviews how innate and adaptive immunity can affect the pathogenesis of ALS and how harnessing the immune system through immunization approaches might offer promising future therapeutic avenues.
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