Your Article Summary
Neutrophils rescue gingival epithelial cells from bacterial-induced apoptosis
Journal of Leukocyte Biology, 07/02/09
Galicia JC et al. - The authros demonstrate here that neutrophils, when combined in a P. gingivalis challenge assay of epithelial cells, prevent epithelial cell apoptosis by phagocytosing P. gingivalis and later undergoing apoptosis themselves. By removing P. gingivalis by phagocytosis, neutrophils also protect the host from the harmful effects of its microbial proteases, which degrade inflammatory cytokines and other host molecules.
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