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Ca2+-dependent mast cell death induced by Ag (I) via cardiolipin oxidation and ATP depletion
Journal of Leukocyte Biology, 07/07/09
Inoue T et al. - These results suggest that Ag (I) activates thiol-dependent Ca2+ channels, thereby promoting Ca2+-dependent CL oxidation, cyt c release, and ATP depletion. This necrotic cell death may play roles in Ag-induced inflammation and autoimmune disorders.
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