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Targeting Tim-1 to overcome resistance to transplantation tolerance mediated by CD8 T17 cells
Proceedings of the National Academy of Sciences of the United States of America, 07/06/09
Yuan X et al. - The data indicate that in the absence of Th1 immunity, CD8 T17 alloreactivity constitutes a barrier to transplantation tolerance. Targeting TIM-1 provides an approach to overcome resistance to tolerance in clinical transplantation.
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