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Douroudis K et al. - The risk alleles and the defined main risk haplotype were more common in the Finnish controls compared with the Estonians, indicating that this gene locus might also be one of the contributing factors to the higher disease incidence in Finland.

Today in Endocrine...keeping you current

Bim-Mediated Apoptosis Is Not Necessary for Thymic Negative Selection to Ubiquitous Self-Antigens
Journal of Immunology, 12/11/09

Control of central self-tolerance induction by autoreactive CD4+ thymocytes
Trends in Immunology, 12/10/09

Autoimmune Regulator Deficiency Results in Decreased Expression of CCR4 and CCR7 Ligands and in Delayed Migration of CD4+ Thymocytes
Journal of Immunology, 12/10/09

Today in Rheumatic/Autoimmune...keeping you current

The sympathetic nervous system modulates CD4+FoxP3+ regulatory T cells via a TGF-[beta]-dependent mechanism
Journal of Leukocyte Biology, 12/15/09

Autoantibodies against C1q in Systemic Lupus Erythematosus Are Antigen-Driven
Journal of Immunology, 12/15/09

Is There a Role for B-cell Depletion as Therapy for Scleroderma? A Case Report and Review of the Literature
Seminars in Arthritis and Rheumatism, 12/15/09