Allergy/Imm Medical News

Become a Member Today!
Register

Most Viewed Abstracts

1. Report Shows Shift in Starting Salaries for Physicians

2. 2008 Exclusive Survey—Earnings: Good news for primary care income

3. Medicare pay-for-reporting effort draws fire from frustrated doctors

4. Debunking Myths in the US Healthcare System

5. Novel therapies for children with severe asthma

Your Article Summary

See Latest Articles

(Click the title below to leave the MDLinx Network and go to the Journal's Website)

Apex2 is required for efficient somatic hypermutation but not for class switch recombination of immunoglobulin genes
International Immunology, 06/26/09

Sabouri Z et al. - Results suggest that Apex2 may play a critical role in SHM through its 3'–5' exonuclease activity. Unexpectedly, the efficiency of CSR was not reduced in Apex2-deficient B cells. In addition, Apex1 knockdown in CH12F3-2 B lymphoma cells did not affect the CSR frequency, suggesting that neither Apex1 nor Apex2 plays a major role in CSR.

<< Previous
Mutational analysis of Cys88 of Toll-like receptor 4 highlights...

Next >>
The Clinical Burden of Tuberculosis Among Human Immunodeficiency...