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See Latest ArticlesApex2 is required for efficient somatic hypermutation but not for class switch recombination of immunoglobulin genes
International Immunology, 06/26/09
Sabouri Z et al. - Results suggest that Apex2 may play a critical role in SHM through its 3'–5' exonuclease activity. Unexpectedly, the efficiency of CSR was not reduced in Apex2-deficient B cells. In addition, Apex1 knockdown in CH12F3-2 B lymphoma cells did not affect the CSR frequency, suggesting that neither Apex1 nor Apex2 plays a major role in CSR.
Today in Basic Science/Genetics...keeping you current
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Innate immune responses to influenza A H5N1: friend or foe
Trends in Immunology, 10/30/09
Mesenchymal Stem Cell Homing Capacity
Transplantation, 10/29/09
Evolution of Bone Disease at 2 Years After Transplantation: A Single-Center Study
Transplantation Proceedings, 11/06/09
Today in Hematology/Oncology...keeping you current
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Randomized phase III trial on gemcitabine versus mytomicin in recurrent superficial bladder cancer: Evaluation of efficacy and tolerance
Journal of Clinical Oncology, 10/23/09
Intratumoral Cytokines and Tumor Cell Biology Determine Spontaneous Breast Cancer–Specific Immune Responses and Their Correlation to Prognosis
Cancer Research, 11/03/09
Factors affecting neutrophil recovery after autologous bone marrow-derived stem cell transplantation in patients with acute myeloid leukemia
Transplantation Proceedings, 11/23/09
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