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Interleukin-17 and Kidney Allograft Outcome
Transplantation Proceedings, 06/26/09

Crispim JCO et al. - Acute rejection episodes (ARE) are important complications that involve the interplay between mechanisms that maintain graft tolerance and promote rejection. The proinflammatory cytokine interleukin-17 (IL-17) has been implicated in many conditions in humans and mice. The findings of this study suggest that IL-17 is important in the pathophysiology of acute kidney rejection.

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