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Identification of new sensitive biomarkers for the in vivo response to interferon-beta treatment in multiple sclerosis using DNA-array evaluation
European Journal of Neurology, 06/24/09
Sellebjerg F et al. - The authors identify IFI27, CCL2 and CXCL10 as sensitive biomarkers for the response to IFN-beta. The expression of these markers adequately reflects bioactivity of IFN-beta as documented by the decreased induction in low NAb-positive patients and the lost induction in patients with moderate/high NAb levels.
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