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See Latest ArticlesHypomorphic mutation of ZAP70 in human results in a late onset immunodeficiency and no autoimmunity
European Journal of Immunology, 06/24/09
Picard C et al. - This partial deficiency results in a compromised TCR signaling that was totally restored by increased expression of ZAP70, demonstrating that defective activation of the patient T cells was indeed caused by the low level of ZAP70 expression. This partial ZAP70 deficiency was associated with an attenuated clinical and immunological phenotype as compared with complete ZAP70 deficiency. CD4+ helper T-cell populations including, follicular helper T cells, Th1, Th17 and Treg were detected in the blood.
Today in Basic Science/Genetics...keeping you current
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T-helper 1 and T-helper 2 adjuvants induce distinct differences in the magnitude, quality and kinetics of the early inflammatory response at the site of injection
Immunology, 12/14/09
Dissociated expression of natural killer 1.1 and T-cell receptor by invariant natural killer T cells after interleukin-12 receptor and T-cell receptor signalling
Immunology, 12/14/09
Inhibition of cyclooxygenase-2 impairs the expression of essential plasma cell transcription factors and human B-lymphocyte differentiation
Immunology, 12/14/09
Today in HIV/Immunodeficiency...keeping you current
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Tuberculous meningitis in HIV-infected patients in Brazil: clinical and laboratory characteristics and factors associated with mortality
International Journal of Infectious Diseases, 12/15/09
Association of HLA-A, B, DRB1 alleles and haplotypes with HIV-1 infection in Chongqing, China
BMC Infectious Diseases, 12/15/09
Cryptic Leishmania infantum infection in Italian HIV infected patients
BMC Infectious Diseases, 12/15/09
Today in Rheumatic/Autoimmune...keeping you current
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Disease Activity and Cytokine Production in Mitogen-Stimulated Peripheral Blood Mononuclear Cells from Patients with Rheumatoid Arthritis
Medical Principles and Practice, 12/14/09
Contribution of a haplotype in the HLA region to anti-cyclic citrullinated peptide antibody positivity in rheumatoid arthritis, independently of HLA-DRB1
Arthritis & Rheumatism, 12/10/09
Normal Regional Lymph Node Enrichment of Antigen-Specific Regulatory T Cells with Autoimmune Disease-Suppressive Capacity
Journal of Immunology, 12/10/09
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