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Intratumoral But Not Systemic Delivery of CpG Oligodeoxynucleotide Augments the Efficacy of Anti-CD20 Monoclonal Antibody Therapy Against B Cell Lymphoma
Journal of Immunotherapy, 06/24/09

Betting DJ et al. - Results suggest that previous clinical trials in B cell lymphoma combining systemic administration of CpG with rituximab may have employed suboptimal routes of CpG delivery. Future trials combining IT CpG with anti-CD20 antibodies or the antibody-mediated targeting of CpG directly to the sites of B cell lymphoma may thus be warranted.

Today in Clinical Pharmacology...keeping you current

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Effects of endogenous glucocorticoids on allergic inflammation and TH1/TH2 balance in airway allergic disease
Annals of Allergy, Asthma, and Immunology, 12/18/09

Meta-analysis of the evidence for a partially hydrolyzed 100% whey formula for the prevention of allergic diseases
Current Medical Research and Opinion, 12/18/09

Non-avian-derived hyaluronan for the treatment of osteoarthritis of the knee
Expert Review of Clinical Immunology, 12/18/09

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Can antigen-specific regulatory T cells protect against graft vs. host disease and spare anti-malignancy alloresponse
Haematologica, 12/18/09

Mutiny on the Boun-T: Controlling Dangerous T Cells Through Anergy
Discovery Medicine, 12/17/09

Immunolocalization and mRNA Expression of Bone Morphogenetic Protein-6 in Human Clear Cell Renal Carcinoma
Kidney and Blood Pressure Research, 12/17/09

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