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Target-dependent T-cell Activation by Coligation With a PSMAxCD3 Diabody Induces Lysis of Prostate Cancer Cells
Journal of Immunotherapy, 06/24/09
Buhler P et al. - Although the diabody binds to all T-cells, only those in contact with PSMA-expressing cancer cells are activated. The PSMA×CD3 diabody is suitable for a controlled polyclonal T-cell therapy of prostate cancer.
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