Allergy/Imm Medical News about Nickel Contact Dermatitis

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Clinical Expression of Nickel Contact Dermatitis Primed by Diagnostic Patch Test
Dermatology, 06/22/09

Hofbauer G et al. - Nickel exposure for 48 h in a patch test is sufficient to induce overt delayed-type hypersensitivity on re-exposure with a previously tolerated antigen in a previously clinically unresponsive individual. Antigen and/or antigen-specific effector cells at the site of previous positive patch testing can be recruited into a delayed-type hypersensitivity reaction for a prolonged period of time.

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