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Systemic Reduction of Functionally Suppressive CD4dimCD25highFoxp3+ Tregs in Human Second Trimester Pregnancy Is Induced by Progesterone and 17 beta-Estradiol
Journal of Immunology, 06/30/09
Mjosberg J et al. - Findings support the view of hormones, particularly progesterone, as critical regulators of Tregs in pregnancy. Furthermore, authors suggest that in the light of the results of this study, early data on circulating Treg frequencies in pregnancy need reevaluation.
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American Journal of Reproductive Immunology, 11/13/09
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