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IRAK4 Kinase Activity Is Required for Th17 Differentiation and Th17-Mediated Disease
Journal of Immunology, 06/29/09
Staschke KA et al. - The results of these studies demonstrate that IL-1-mediated IRAK4 kinase activity in T cells is essential for induction of IL-23R expression, Th17 differentiation, and autoimmune disease.
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