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Staschke KA et al. - The results of these studies demonstrate that IL-1-mediated IRAK4 kinase activity in T cells is essential for induction of IL-23R expression, Th17 differentiation, and autoimmune disease.

Today in Rheumatic/Autoimmune...keeping you current

The sympathetic nervous system modulates CD4+FoxP3+ regulatory T cells via a TGF-[beta]-dependent mechanism
Journal of Leukocyte Biology, 12/15/09

Autoantibodies against C1q in Systemic Lupus Erythematosus Are Antigen-Driven
Journal of Immunology, 12/15/09

Is There a Role for B-cell Depletion as Therapy for Scleroderma? A Case Report and Review of the Literature
Seminars in Arthritis and Rheumatism, 12/15/09