Cross-cohort heterogeneity encountered while validating a model for HIV disease progression among antiretroviral initiators
Journal of Clinical Epidemiology, 06/05/2009
Shepherd BE et al. - The model was fair at using baseline characteristics to order patients' risk of disease progression, but did not accurately predict AIDS-free survival >3 years after HAART initiation. Different variable definitions, patient characteristics, and loss to follow-up highlight the challenges of using data from one cohort to predict AIDS-free survival in an independent cohort.






