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Primary ovarian insufficiency: X chromosome defects and autoimmunity
Journal of Autoimmunity , 06/11/09
Persani L et al. - Heterogeneity of POI is reflected by the variety of possible causes, including autoimmunity, toxics, drugs, as well as genetic defects. Several data indicate that POI has a strong genetic component. In this manuscript authors discuss the X chromosome abnormalities that are associated with POI.
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