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See Latest ArticlesMicroheterogeneous monoclonal antibody subspecies with differential hepatitis C virus core antigen binding properties identified by SEC-HPLC
Journal of Immunological Methods, 06/10/09
Muerhoff AS et al. - Results suggest that this monoclonal antibody consists of microheterogeneous subspecies that exhibit different antigen binding properties associated with differences in post-translational modification of the heavy chain variable region. The choice of size exclusion column matrix and buffer composition was critical to the identification of these monoclonal IgG subspecies.
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