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See Latest ArticlesEndoplasmic reticulum stress in the intestinal epithelium and inflammatory bowel disease
Seminars in Immunology, 06/05/09
Kaser A et al. - An inability to manage ER stress may not only be a primary originator of intestinal inflammation as exemplified by genetic polymorphisms in XBP1 that are associated with IBD but also a perpetuator of inflammation when ER stress is induced secondarily to inflammatory mediators or microbial factors. Furthermore, ER stress pathways may interact with other processes that lead to IBD, notably autophagy.
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